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PTK6 (Human) Recombinant ProteinBioActive

  • Catalog # : P4192
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  • Specification
  • Product Description:
  • Human PTK6 (NM_005975) full-length recombinant protein with GST tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 80
  • Form:
  • Liquid
  • Purity:
  • >= 95% by SDS-PAGE
  • Activity:
  • 133 nmol phosphate incorporated into Poly (Glu-Tyr) per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 uM ATP and total of 0.83 uCi/uL P-32.
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 5753
  • Gene Name:
  • PTK6
  • Gene Alias:
  • BRK,FLJ42088
  • Gene Description:
  • PTK6 protein tyrosine kinase 6
  • Gene Summary:
  • The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031656,breast tumor kinase,protein-tyrosine kinase BRK
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