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GSK3B (Human) Recombinant ProteinBioActive

  • Catalog # : P4183
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  • Specification
  • Product Description:
  • Human GSK3B (P49841) full-length recombinant protein with His tag expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 53.0-56.0
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • >= 90% by SDS-PAGE
  • Activity:
  • Activity of GSK-3beta was determined by an in vitro kinase assay using 100 ng Tau as substrate and 1 ug of the recombinant GSK-3beta in a 20 uL reaction containing 25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerol phosphate, 12 mM MgCl2, 2 mM DTT, 0.1
  • Storage Buffer:
  • Lyophilized from 2 mg/mL in 0.1 M NH4CO3
  • Storage Instruction:
  • Store at -80°C on dry atmosphere.
    After reconstitution with PBS containing 15% glycerol, store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 2932
  • Gene Name:
  • GSK3B
  • Gene Alias:
  • -
  • Gene Description:
  • glycogen synthase kinase 3 beta
  • Gene Summary:
  • The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
  • Other Designations:
  • GSK3beta isoform,glycogen synthase kinase-3 beta
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  • Interactome
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