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BMP6 (Human) Recombinant ProteinBioActive

  • Catalog # : P4163
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  • Specification
  • Product Description:
  • Human BMP6 (P22004, 142 amino acids) partial recombinant protein expressed in Escherichia coli. This protein has two forms, monomer (15 KDa) and dimer (30 KDa).
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 15, 30
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • >= 98% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug
  • Activity:
  • This recombinant human BMP-6 is biologically active.The ED50 as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 ug/mL.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized 20 mM acetic acid, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 654
  • Gene Name:
  • BMP6
  • Gene Alias:
  • VGR,VGR1
  • Gene Description:
  • bone morphogenetic protein 6
  • Gene Summary:
  • The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016006,Vg1-related sequence,vegetal related growth factor (TGFB-related),vegetal-related (TGFB related) cytokine
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