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NAMPT (Human) Recombinant ProteinBioActive

  • Catalog # : P4162
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  • Specification
  • Product Description:
  • Human NAMPT (P43490) full-length recombinant protein expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 55
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • >= 95% by SDS-PAGE
  • Endotoxin Level:
  • < 0.1 ng/ug
  • Activity:
  • Mimics insulin effects in differentiating 3T3-L1 cells.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with PBS, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Gene Name:
  • NAMPT
  • Gene Alias:
  • 1110035O14Rik,DKFZp666B131,MGC117256,PBEF,PBEF1,VF,VISFATIN
  • Gene Description:
  • nicotinamide phosphoribosyltransferase
  • Gene Summary:
  • This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This gene has a pseudogene on chromosome 10. [provided by RefSeq
  • Other Designations:
  • NAmPRTase,pre-B cell-enhancing factor,pre-B-cell colony enhancing factor 1
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