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BMPR1A (Human) Recombinant ProteinBioActive

  • Catalog # : P4155
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  • Specification
  • Product Description:
  • Human BMPR1A (P36894) partial recombinant protein expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 23
  • Form:
  • Lyophilized
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • >= 90% by SDS-PAGE and HPLC
  • Activity:
  • Measured by its ability to inhibit recombinant human BMP-2 induced alkaline phosphatase production by C2C12 myogenic cells.The ED50 for this effect is typically 1-3 ug/mL in the presence of 500 ng/mL of recombinant human BMP-2.
  • Storage Buffer:
  • Lyophilized from 1X PBS
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized PBS, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 657
  • Gene Name:
  • BMPR1A
  • Gene Alias:
  • 10q23del,ACVRLK3,ALK3,CD292
  • Gene Description:
  • bone morphogenetic protein receptor, type IA
  • Gene Summary:
  • The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020014,activin A receptor, type II-like kinase 3
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