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Last updated: 2016/12/4

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LEP (Human) Recombinant ProteinBioActive

  • Catalog # : P4102
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  • Specification
  • Product Description:
  • Human LEP (NP_002294.2, 1 a.a. - 839 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 130-140
  • Form:
  • Lyophilized
  • Purity:
  • >= 98% by SDS-PAGE and HPLC
  • Activity:
  • Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.
  • Storage Buffer:
  • Lyophilized from 0.0045 mM NaHCO3
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3952
  • Gene Name:
  • LEP
  • Gene Alias:
  • FLJ94114,OB,OBS
  • Gene Description:
  • leptin
  • Gene Summary:
  • This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq
  • Other Designations:
  • leptin (murine obesity homolog),leptin (obesity homolog, mouse),obese, mouse, homolog of,obesity factor
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