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TNFRSF9 (Human) Recombinant ProteinBioActive

  • Catalog # : P4066
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  • Specification
  • Product Description:
  • Human TNFRSF9 (NP_001552, 167 amino acids) partial recombinant protein expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 17.8
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • >= 98% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug
  • Activity:
  • Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inhibition was seen using a concentration of 1 ug for both 4-1BBL and 4-1BBR.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3604
  • Gene Name:
  • TNFRSF9
  • Gene Alias:
  • 4-1BB,CD137,CDw137,ILA,MGC2172
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 9
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq
  • Other Designations:
  • 4-1BB ligand receptor,CD137 antigen,OTTHUMP00000001360,OTTHUMP00000044294,T cell antigen ILA,homolog of mouse 4-1BB,induced by lymphocyte activation (ILA),interleukin-activated receptor, homolog of mouse Ly63,receptor protein 4-1BB
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