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Last updated: 2017/7/16

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PF4 (Human) Native ProteinBioActive

  • Catalog # : P4061
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  • Specification
  • Product Description:
  • Human PF4 (P02776, 70 amino acids) native protein from human platelets.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 7.8
  • Form:
  • Lyophilized
  • Preparation Method:
  • Native protein purified from human platelets
  • Purity:
  • >= 95% by SDS-PAGE and HPLC
  • Activity:
  • Binding of HIT-antibodies.
  • Storage Buffer:
  • Lyophilized from PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 5196
  • Gene Name:
  • PF4
  • Gene Alias:
  • CXCL4,MGC138298,SCYB4
  • Gene Description:
  • platelet factor 4
  • Gene Summary:
  • Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).[supplied by OMIM
  • Other Designations:
  • chemokine (C-X-C motif) ligand 4,platelet factor 4 (chemokine (C-X-C motif) ligand 4)
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