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Last updated: 2017/3/19

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CTSB (Human) Native ProteinBioActive

  • Catalog # : P4029
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  • Specification
  • Product Description:
  • Human CTSB (P07858) native protein from human liver.
  • Host:
  • Human
  • Form:
  • Liquid
  • Preparation Method:
  • Native protein purified from human liver
  • Purity:
  • >= 95% by SDS-PAGE
  • Activity:
  • 470 units/mg
  • Storage Buffer:
  • In 50 mM sodium acetate, 1 mM EDTA, pH 5.0
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 1508
  • Gene Name:
  • CTSB
  • Gene Alias:
  • APPS,CPSB
  • Gene Description:
  • cathepsin B
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • APP secretase,OTTHUMP00000116009,amyloid precursor protein secretase,cathepsin B1,cysteine protease,preprocathepsin B
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