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IL5 (Human) Recombinant ProteinBioActive

  • Catalog # : P3990
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  • Specification
  • Product Description:
  • Human IL5 (P05113, 232 amino acids) partial recombinant protein expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 26.5
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • >= 98% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug
  • Activity:
  • The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 0.15 ng/mL, corresponding to a specific activity of > 6 x 106 units/mg.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3567
  • Gene Name:
  • IL5
  • Gene Alias:
  • EDF,IL-5,TRF
  • Gene Description:
  • interleukin 5 (colony-stimulating factor, eosinophil)
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq
  • Other Designations:
  • B cell differentiation factor I,OTTHUMP00000065830,T-cell replacing factor,eosinophil differentiation factor,interleukin 5,interleukin-5
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