Human CCL1 (P22362, 74 amino acids) partial recombinant protein expressed in Escherichia coli.
Theoretical MW (kDa):
Escherichia coli expression system
>= 98% by SDS-PAGE and HPLC
< 0.1 ng/ug
The biological activity of the recombinant human I-309 was determined by a chemotaxis assay using total human T cell popμlation. Significant chemotaxis was achieved at a concentration range of 1-100 ng/mL.
Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq
T lymphocyte-secreted protein I-309,inflammatory cytokine I-309,small inducible cytokine A1,small inducible cytokine A1 (I-309, homologous to mouse Tca-3)