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FGF18 (Human) Recombinant ProteinBioActive

  • Catalog # : P3971
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  • Specification
  • Product Description:
  • Human FGF18 (O76093, 182 amino acids) partial recombinant protein expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 21.2
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • >= 95% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug
  • Activity:
  • The ED50 was determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is < 0.5 ng/mL, corresponding to a specific activity of > 2 x 106 units/mg.
  • Storage Buffer:
  • Lyophilized from 10 mM Tris pH 8.0
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 5 mM Tris, store at 4°C for 1 week or -20°C for longer.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 8817
  • Gene Name:
  • FGF18
  • Gene Alias:
  • FGF-18,ZFGF5
  • Gene Description:
  • fibroblast growth factor 18
  • Gene Summary:
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq
  • Other Designations:
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