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TEK (Human) Recombinant ProteinBioActive

  • Catalog # : P3926
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  • Specification
  • Product Description:
  • Human TEK (NM_000459, 771 a.a. - end) partial recombinant protein with GST tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 61
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • > 90% by densitometry
  • Activity:
  • The specific activity was determined to be 12 nmol /min/mg as per Activity Assay Protocol.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P3926
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 7010
  • Gene Name:
  • TEK
  • Gene Alias:
  • CD202B,TIE-2,TIE2,VMCM,VMCM1
  • Gene Description:
  • TEK tyrosine kinase, endothelial
  • Gene Summary:
  • The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021167,soluble TIE2 variant 1,soluble TIE2 variant 2
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