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STK4 (Human) Recombinant ProteinBioActive

  • Catalog # : P3923
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  • Specification
  • Product Description:
  • Human STK4 (NM_006282) full-length recombinant protein with GST tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 83
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • > 85% by densitometry
  • Activity:
  • The specific activity was determined to be 1120 nmol /min/mg as per Activity Assay Protocol.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P3923
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6789
  • Gene Name:
  • STK4
  • Gene Alias:
  • DKFZp686A2068,KRS2,MST1,YSK3
  • Gene Description:
  • serine/threonine kinase 4
  • Gene Summary:
  • The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000043418,dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)),kinase responsive to stress 2,mammalian sterile 20-like 1,yeast Ste20-like
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