Product Browser

Last updated: 2016/12/4

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

ROCK1 (Human) Recombinant ProteinBioActive

  • Catalog # : P3913
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Human ROCK1 (NM_005406, 17 a.a. - 535 a.a.) partial recombinant with GST tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 85
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • > 90% by densitometry
  • Activity:
  • The specific activity was determined to be 65 nmol /min/mg as per Activity Assay Protocol.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P3913
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6093
  • Gene Name:
  • ROCK1
  • Gene Alias:
  • MGC131603,MGC43611,P160ROCK,PRO0435
  • Gene Description:
  • Rho-associated, coiled-coil containing protein kinase 1
  • Gene Summary:
  • This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000162514,p160-ROCK
  • RSS
  • YouTube
  • Linkedin
  • Facebook