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ITK (Human) Recombinant ProteinBioActive

  • Catalog # : P3870
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  • Specification
  • Product Description:
  • Human ITK (NM_005546, 352 a.a. - end) partial recombinant protein with GST tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 53
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • > 90% by densitometry
  • Activity:
  • The specific activity was determined to be 58 nmol /min/mg as per Activity Assay Protocol.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P3870
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3702
  • Gene Name:
  • ITK
  • Gene Alias:
  • EMT,LYK,MGC126257,MGC126258,PSCTK2
  • Gene Description:
  • IL2-inducible T-cell kinase
  • Gene Summary:
  • This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq
  • Other Designations:
  • homolog of mouse T-cell itk/tsk,tyrosine-protein kinase ITK/TSK,tyrosine-protein kinase LYK
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