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BTK (Human) Recombinant ProteinBioActive

  • Catalog # : P3843
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  • Specification
  • Product Description:
  • Human BTK (NM_000061) full-length recombinant protein with His tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 78
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • > 90% by densitometry
  • Activity:
  • The specific activity was determined to be 43 nmol /min/mg as per Activity Assay Protocol.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P3843
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 695
  • Gene Name:
  • BTK
  • Gene Alias:
  • AGMX1,AT,ATK,BPK,IMD1,MGC126261,MGC126262,PSCTK1,XLA
  • Gene Description:
  • Bruton agammaglobulinemia tyrosine kinase
  • Gene Summary:
  • The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq
  • Other Designations:
  • B-cell progenitor kinase,Bruton tyrosine kinase,OTTHUMP00000023676,OTTHUMP00000063593,agammaglobulinemia tyrosine kinase,dominant-negative kinase-deficient Brutons tyrosine kinase,tyrosine-protein kinase BTK
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