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BMX (Human) Recombinant ProteinBioActive

  • Catalog # : P3842
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  • Specification
  • Product Description:
  • Human BMX (NM_001721) full-length recombinant protein with GST tag expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 110
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • > 80% by densitometry
  • Activity:
  • The specific activity was determined to be 34 nmol/min/mg as per Activity Assay Protocol.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P3842
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 660
  • Gene Name:
  • BMX
  • Gene Alias:
  • ETK,PSCTK2,PSCTK3
  • Gene Description:
  • BMX non-receptor tyrosine kinase
  • Gene Summary:
  • This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified
  • Other Designations:
  • OTTHUMP00000022964,OTTHUMP00000022965,OTTHUMP00000022966
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