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Last updated: 2016/10/16

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HGF (Human) Recombinant Protein

  • Catalog # : P3805
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  • Specification
  • Product Description:
  • Human HGF (NP_000592.3, 32 a.a. - 494 a.a.) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • Host:
  • Escherichia coli
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 95% by SDS-PAGE
  • Quality Control Testing:
  • 10% SDS-PAGE Result

    QC Testing of P3805
  • Storage Buffer:
  • In PBS (50% glycerol)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3082
  • Gene Name:
  • HGF
  • Gene Alias:
  • Gene Description:
  • hepatocyte growth factor (hepapoietin A; scatter factor)
  • Gene Summary:
  • Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • fibroblast-derived tumor cytotoxic factor,hepatocyte growth factor,hepatopoietin A,lung fibroblast-derived mitogen,scatter factor
  • Interactome
  • Interactome
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