Products

SDS-PAGE

Entrez GeneID

Protein Accession#

Gene Name

ADAMTS10

Gene Alias

ADAM-TS10, WMS

Gene Description

ADAM metallopeptidase with thrombospondin type 1 motif, 10

Omim ID

Gene Ontology

Gene Summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq

Other Designations

Weill-Marchesani syndrome|a disintegrin and metalloproteinase with thrombospondin motifs 10|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10|a disintegrin-like and metalloprotease domain with thrombospondin typ