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LIFR (Human) Recombinant Protein

  • Catalog # : P3681
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  • Specification
  • Product Description:
  • Human LIFR (P42702, Gln 45 - Ser 833) partial recombinant protein expressed in HEK293 cells.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 125-135
  • Form:
  • Lyophilized
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Purification:
  • Ion exchange column and HPLC reverse phase column
  • Purity:
  • > 90% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug (1 EU/ug)
  • Storage Buffer:
  • Lyophilized from PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3977
  • Gene Name:
  • LIFR
  • Gene Alias:
  • CD118,FLJ98106,FLJ99923,LIF-R,SJS2,STWS,SWS
  • Gene Description:
  • leukemia inhibitory factor receptor alpha
  • Gene Summary:
  • This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD118 antigen,leukemia inhibitory factor receptor
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