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CCL23 (Human) Recombinant ProteinBioActive

  • Catalog # : P3653
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human CCL23 (P55773 , 22 a.a. - 120 a.a.) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • RVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 11
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Ion exchange column and HPLC reverse phase column
  • Purity:
  • > 90% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug (1 EU/ug)
  • Activity:
  • Determined by its ability to chemoattract human T cells using a concentration range of 2.0-40.0 ng/mL.
  • Storage Buffer:
  • Lyophilized from 20 mM PB, 100 mM NaCl, pH 7.5
  • Storage Instruction:
  • Store at -20°C on dry atmosphere for 2 years.
    After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6368
  • Gene Name:
  • CCL23
  • Gene Alias:
  • CK-BETA-8,CKb8,Ckb-8,Ckb-8-1,MIP-3,MIP3,MPIF-1,SCYA23
  • Gene Description:
  • chemokine (C-C motif) ligand 23
  • Gene Summary:
  • This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • C6 beta-chemokine,OTTHUMP00000163948,hmrp-2a,macrophage inflammatory protein 3,myeloid progenitor inhibitory factor 1,small inducible cytokine A23,small inducible cytokine subfamily A (Cys-Cys), member 23
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