Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/mL.
Storage Buffer:
Lyophilized from PBS, pH 7.5
Storage Instruction:
Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988 [PubMed 3279154]). Sherry et al. (1988) [PubMed 3058856] demonstrated 2 protein components of MIP1, called by them alpha and beta.[supplied by OMIM
Other Designations:
LD78 alpha beta,small inducible cytokine A3 (homologous to mouse Mip-1a)