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IL31 (Human) Recombinant ProteinBioActive

  • Catalog # : P3637
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  • Specification
  • Product Description:
  • Human IL31 (Q6EBC2, 24 a.a. - 164 a.a.) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • SHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 18
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Ion exchange column and HPLC reverse phase column
  • Purity:
  • > 90% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug (1 EU/ug)
  • Activity:
  • The ED50 was determined by the ability to induce STAT3 activation in U87MG cells, and was determined to be not less than 7 ng/mL.
  • Storage Buffer:
  • Lyophilized from PBS, pH 7.5
  • Storage Instruction:
  • Store at -20°C on dry atmosphere for 2 years.
    After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Gene Name:
  • IL31
  • Gene Alias:
  • IL-31
  • Gene Description:
  • interleukin 31
  • Gene Summary:
  • IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM
  • Other Designations:
  • -
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