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IL1A (Human) Recombinant ProteinBioActive

  • Catalog # : P3627
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  • Specification
  • Product Description:
  • Human IL1A (P01583, 113 a.a. - 271 a.a.) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • SAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 18
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Ion exchange column and HPLC reverse phase column
  • Purity:
  • > 90% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug (1 EU/ug)
  • Activity:
  • The ED50 was determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/mL, corresponding to a specific activity of ≥ 2 x 109 units/mg
  • Storage Buffer:
  • Lyophilized from PBS, pH 7.0
  • Storage Instruction:
  • Store at -20°C on dry atmosphere for 2 years.
    After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3552
  • Gene Name:
  • IL1A
  • Gene Alias:
  • IL-1A,IL1,IL1-ALPHA,IL1F1
  • Gene Description:
  • interleukin 1, alpha
  • Gene Summary:
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq
  • Other Designations:
  • IL1A (IL1F1),hematopoietin-1,preinterleukin 1 alpha,pro-interleukin-1-alpha
  • Related Disease
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