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SCYE1 (Human) Recombinant ProteinBioActive

  • Catalog # : P3601
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  • Specification
  • Product Description:
  • Human SCYE1 (Q12904, 1 a.a. - 312 a.a.) full-length recombinant protein. expressed in Escherichia coli.
  • Sequence:
  • MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 18
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Ion exchange column and HPLC reverse phase column
  • Purity:
  • > 90% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug (1 EU/ug)
  • Activity:
  • The ED50 was determined by apoptotic effect on MCF-7 cells using a concentration of 10-50 ng/mL.
  • Storage Buffer:
  • Lyophilized from 20 mM PB, 130 mM NaCl, pH 7.5
  • Storage Instruction:
  • Store at -20°C on dry atmosphere for 2 years.
    After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 9255
  • Gene Name:
  • SCYE1
  • Gene Alias:
  • AIMP1,EMAP2,EMAPII,p43
  • Gene Description:
  • small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq
  • Other Designations:
  • ARS-interacting multifunctional protein 1,OTTHUMP00000161878,endothelial monocyte-activating polypeptide 2,endothelial-monocyte activating polypeptide II,multisynthetase complex auxiliary component p43,small inducible cytokine subfamily E, member 1
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