CTNNBIP1 (Human) Recombinant Protein
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Specification
Product Description
Human CTNNBIP1 (NP_064633, 1 a.a. - 81 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMNREGAPGKSPEEMYIQQKVRVLLMLRKMGSNLTASEEEFLRTYAGVVNSQLSQLPPHSIDQGAEDVVMAFSRSETEDRRQ
Host
Escherichia coli
Theoretical MW (kDa)
11.3
Form
Liquid
Preparation Method
Escherichia coli expression system
Purification
Conventional Chromatography
Concentration
1 mg/mL
Purity
> 90% by SDS-PAGE
Quality Control Testing
Loading 3 ug protein in 15% SDS-PAGE
Storage Buffer
In 20 mM Tris-HCl buffer, 100 mM NaCl, pH 8.0 (20% glycerol, 2 mM DTT).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — CTNNBIP1
Entrez GeneID
56998Protein Accession#
NP_064633Gene Name
CTNNBIP1
Gene Alias
ICAT, MGC15093
Gene Description
catenin, beta interacting protein 1
Omim ID
607758Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000001722|OTTHUMP00000001723|OTTHUMP00000001724|OTTHUMP00000001725|beta-catenin-interacting protein ICAT|catenin, beta-interacting protein 1|inhibitor of beta-catenin and Tcf-4
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Interactome
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Pathway
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