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Last updated: 2016/12/11

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PHLDA2 (Human) Recombinant Protein

  • Catalog # : P3550
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  • Specification
  • Product Description:
  • Human PHLDA2 (NP_003302, 1 a.a. - 152 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
  • Sequence:
  • MGSSHHHHHHSSGLVPRGSHMKSPDEVLREGELEKRSDSLFQLWKKKRGVLTSDRLSLFPASPRARPKELRFHSILKVDCVERTGKYVYFTIVTTDHKEIDFRCAGESCWNAAIALALIDFQNRRALQDFRSRQERTAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPRTP
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 19.2
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Conventional Chromatography
  • Concentration:
  • 0.5 mg/mL
  • Purity:
  • > 80% by SDS-PAGE
  • Quality Control Testing:
  • Loading 3 ug protein in 15% SDS-PAGE

    QC Testing of P3550
  • Storage Buffer:
  • In 20 mM Tris-HCl, 0.1M NaCl, pH 8.0 (1 mM dithiothreitol, 20% glycerol)
  • Storage Instruction:
  • Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 7262
  • Gene Name:
  • PHLDA2
  • Gene Alias:
  • BRW1C,BWR1C,HLDA2,IPL,TSSC3
  • Gene Description:
  • pleckstrin homology-like domain, family A, member 2
  • Gene Summary:
  • This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth. [provided by RefSeq
  • Other Designations:
  • imprinted in placenta and liver,p17-Beckwith-Wiedemann region 1C,pleckstrin homology-like domain family A member 2,tumor suppressing subchromosomal transferable fragment cDNA 3,tumor suppressing subtransferable candidate 3,tumor-supressing STF cDNA 3
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