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PRDX6 (Human) Recombinant Protein BioActive

  • Catalog # : P3491
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  • Specification
  • Product Description:
  • Human PRDX6 (NP_004896, 1 a.a. - 224 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
  • Sequence:
  • MGSSHHHHHHSSGLVPRGSHMPGGLLLGDVAPNFEANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVLPTIPEEEAKKLFPKGVFTKELPSGKKYLRYTPQP
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 27.1
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Conventional Chromatography
  • Concentration:
  • 1 mg/mL
  • Purity:
  • > 95% by SDS-PAGE
  • Activity:
  • Specific activity: approximately 95-120 pmole/min/ug. Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX6 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25°C for 1 minute.
  • Quality Control Testing:
  • Loading 3 ug protein in 15% SDS-PAGE

    QC Testing of P3491
  • Storage Buffer:
  • In 20 mM Tris-HCl buffer, pH 8.0 (20% glycerol).
  • Storage Instruction:
  • Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 9588
  • Gene Name:
  • PRDX6
  • Gene Alias:
  • 1-Cys,AOP2,KIAA0106,MGC46173,NSGPx,PRX,aiPLA2,p29
  • Gene Description:
  • peroxiredoxin 6
  • Gene Summary:
  • The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq
  • Other Designations:
  • 1-Cys peroxiredoxin,OTTHUMP00000032693,acidic calcium-independent phospholipase A2,antioxidant protein 2,non-selenium glutathione peroxidase
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