VAMP2 (Human) Recombinant Protein
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Specification
Product Description
Human VAMP2 (NP_055047, 1 a.a. - 89 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.
Sequence
MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSHMSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYW
Host
Escherichia coli
Theoretical MW (kDa)
13.8
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS-PAGE
Quality Control Testing
3 ug by 15% SDS-PAGE under reducing condition and visualized by Coomassie blue stain.
Storage Buffer
In PBS, pH 7.4 (1 mM EDTA).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — VAMP2
Entrez GeneID
6844Protein Accession#
NP_055047Gene Name
VAMP2
Gene Alias
FLJ11460, SYB2, VAMP-2
Gene Description
vesicle-associated membrane protein 2 (synaptobrevin 2)
Omim ID
185881Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq
Other Designations
synaptobrevin 2|vesicle associated membrane protein 2
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Interactome
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