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Last updated: 2016/12/4
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PDGFRB monoclonal antibody, clone 18A2 (APC)

  • Catalog # : MAB9990
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against PDGFRB.
  • Immunogen:
  • CD140b-transfected NIH 3T3 cells.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • PDGFRB, the 180-190 kDa betachain of platelet-derived growth factor receptor, which is widely expressed on a variety ofmesenchymal-derived cells and plays pro-proliferative roles.
  • Form:
  • Liquid
  • Conjugation:
  • APC
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow cytometry (10 ul reagent / 100 ul of whole blood or 106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide, 0.2% (w/v) BSA)
  • Storage Instruction:
  • Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 5159
  • Gene Name:
  • PDGFRB
  • Gene Alias:
  • CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1
  • Gene Description:
  • platelet-derived growth factor receptor, beta polypeptide
  • Gene Summary:
  • This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
  • Other Designations:
  • beta platelet-derived growth factor receptor,platelet-derived growth factor receptor beta,soluble PDGFRb variant 1
  • Interactome
  • Interactome
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