ALDOB monoclonal antibody, clone 10
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant ALDOB.
Immunogen
Recombinant protein corresponding to full length human ALDOB.
Host
Mouse
Reactivity
Human
Specificity
It can expression in HEK293 whole cell lysate.
Form
Liquid
Purification
Affinity purification
Isotype
IgG2a
Recommend Usage
Western blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of HEK293 whole cell lystae with ALDOB monoclonal antibody, clone 10 (Cat # MAB9949) at 1:500 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ALDOB
Entrez GeneID
229GeneBank Accession#
NM_000035Protein Accession#
NP_000026.2Gene Name
ALDOB
Gene Alias
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Gene Description
aldolase B, fructose-bisphosphate
Omim ID
229600Gene Ontology
HyperlinkGene Summary
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq
Other Designations
OTTHUMP00000021803|aldolase 2|aldolase B, fructose-bisphosphatase
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Carbon fixation in photosynthetic organisms
- Fructose and mannose metabolism
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