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Last updated: 2016/11/27

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RPSA monoclonal antibody, clone 16

  • Catalog # : MAB9942
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant RPSA.
  • Immunogen:
  • Recombinant protein corresponding to full length human RPSA.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • It can expression in HeLa whole cell lysate.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Western blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa whole cell lystae with RPSA monoclonal antibody, clone 16 (Cat # MAB9942 ).
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3921
  • Gene Name:
  • RPSA
  • Gene Alias:
  • 37LRP,67LR,LAMBR,LAMR1,LRP,p40
  • Gene Description:
  • ribosomal protein SA
  • Gene Summary:
  • Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 67kD, ribosomal protein SA,laminin receptor 1 (67kD, ribosomal protein SA)
  • Gene Pathway
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