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XRCC5 monoclonal antibody, clone 6

  • Catalog # : MAB9925
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant XRCC5.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-210 of human XRCC5.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • It can expression in SW480 whole cell lysate.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Western blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of SW480 whole cell lystae with XRCC5 monoclonal antibody, clone 6 (Cat # MAB9925) at 1:1000 dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7520
  • Gene Name:
  • XRCC5
  • Gene Alias:
  • FLJ39089,KARP-1,KARP1,KU80,KUB2,Ku86,NFIV
  • Gene Description:
  • X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
  • Gene Summary:
  • The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq
  • Other Designations:
  • ATP-dependent DNA helicase II,DNA repair protein XRCC5,Ku autoantigen, 80kDa,Ku86 autoantigen related protein 1,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD),X-ray repair, comp
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