HP monoclonal antibody, clone 1
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant HP.
Immunogen
Recombinant protein corresponding to amino acids 19-406 of human HP.
Host
Mouse
Reactivity
Human
Specificity
It can expression in BGC823 whole cell lysate.
Form
Liquid
Purification
Affinity purification
Purity
90%
Isotype
IgG1
Recommend Usage
Western blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of BGC-823 whole cell lystae with HP monoclonal antibody, clone 1 (Cat # MAB9895) at 1:1000 dilution.Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — HP
Entrez GeneID
3240GeneBank Accession#
NM_001126102Protein Accession#
NP_001119574Gene Name
HP
Gene Alias
BP, HP2-ALPHA-2, HPA1S, MGC111141
Gene Description
haptoglobin
Omim ID
140100Gene Ontology
HyperlinkGene Summary
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
binding peptide|haptoglobin alpha(1S)-beta|haptoglobin alpha(2FS)-beta|haptoglobin, alpha polypeptide|haptoglobin, beta polypeptide
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