SERPINE1 monoclonal antibody, clone 10
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant SERPINE1.
Immunogen
Recombinant protein corresponding to full length human SERPINE1.
Host
Mouse
Reactivity
Human
Specificity
It can expression in BGC823 whole cell lysate.
Form
Liquid
Purification
Affinity purification
Isotype
IgG2b
Recommend Usage
Western blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of BGC-823 whole cell lystae with SERPINE1 monoclonal antibody, clone 10 (Cat # MAB9890) at 1:500 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SERPINE1
Entrez GeneID
5054GeneBank Accession#
NM_000602.3Protein Accession#
NP_000593.1Gene Name
SERPINE1
Gene Alias
PAI, PAI-1, PAI1, PLANH1
Gene Description
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Omim ID
173360Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
plasminogen activator inhibitor, type I|plasminogen activator inhibitor-1|serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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Interactome
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Pathway
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Disease
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