MS4A1 monoclonal antibody, clone 2H7 (FITC)

Catalog # MAB9849

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Price

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Quantity

Size:100 Reactions
Price: USD $ 329.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Mouse monoclonal antibody raised against MS4A1.

    Immunogen

    Human tonsillar B cells.

    Host

    Mouse

    Theoretical MW (kDa)

    33-37

    Reactivity

    Human, Non-Human Primates

    Specificity

    The mouse monoclonal antibody 2H7 recognizes MS4A1 (CD20), a 33-37 kDa non-glycosylated membrane receptor with four transmembrane domains, expressed on pre-B lymphocytes, resting and activated B cells (not plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.

    Form

    Liquid

    Conjugation

    FITC

    Isotype

    IgG2b

    Recommend Usage

    Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4 (0.02% BSA, 0.09% sodium azide)

    Storage Instruction

    Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Flow Cytometry

  • Gene Info — MS4A1

    Entrez GeneID

    931

    Gene Name

    MS4A1

    Gene Alias

    B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7

    Gene Description

    membrane-spanning 4-domains, subfamily A, member 1

    Omim ID

    112210

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq

    Other Designations

    B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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