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Last updated: 2017/8/20
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CD3 (activation epitope) monoclonal antibody, clone APA1/1 (PE)

  • Catalog # : MAB9820
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD3.
  • Immunogen:
  • Native purified CD3 from human thymus.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Purification:
  • Size-exclusion chromatography purification
  • Concentration:
  • 0.1 mg/mL
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
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