KRT17 monoclonal antibody, clone V21-R
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of KRT17.
Immunogen
A synthetic peptide corresponding to C-terminus of human KRT17.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM Tris-HCl, pH 8.0 (20 mg/mL BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human squamous skin carcinoma (A, 4 µm), and human breast tissue (B, 4 µm), stained with KRT17 monoclonal antibody, clone V21-R (Cat # MAB9768) shows strong positive cytoplasmic immunostaining of tumor cells (A), and strong positive cytoplasmic immunostaining of myoepithelial cells in hyperplastic duct (B).
Kindly performed and provided by Katarina Poliakova, MD and L'ubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovak republic.Immunohistochemistry (Frozen sections)
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Gene Info — KRT17
Entrez GeneID
3872Protein Accession#
Q04695Gene Name
KRT17
Gene Alias
K17, PC, PC2, PCHC1
Gene Description
keratin 17
Gene Ontology
HyperlinkGene Summary
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq
Other Designations
cytokeratin-17
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