Formalin-fixed and paraffin-embedded human squamous skin carcinoma (A, 4 µm), and human breast tissue (B, 4 µm), stained with KRT17 monoclonal antibody, clone V21-R (Cat # MAB9768) shows strong positive cytoplasmic immunostaining of tumor cells (A), and strong positive cytoplasmic immunostaining of myoepithelial cells in hyperplastic duct (B). Kindly performed and provided by Katarina Poliakova, MD and L'ubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovak republic.
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq