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Last updated: 2017/10/15

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PTS monoclonal antibody, clone AT2B2

  • Catalog # : MAB9721
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant PTS.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-145 of human PTS.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • ELISA (1:500)
    Western Blot (1:250-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of mouse kidney lysates (Lane 1, 40 ug) and recombinant protein (Lane 2 is 1000 ng; Lane 3 is 500 ng) with PTS monoclonal antibody, clone AT2B2 (Cat # MAB9721) at 1 : 500 dilution. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5805
  • Gene Name:
  • PTS
  • Gene Alias:
  • FLJ97081,PTPS
  • Gene Description:
  • 6-pyruvoyltetrahydropterin synthase
  • Gene Summary:
  • The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq
  • Other Designations:
  • 6-pyruvoyl tetrahydrobiopterin synthase,6-pyruvoyl-tetrahydropterin synthase,PTP synthase
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