THBD monoclonal antibody, clone 15C8
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant THBD.
Immunogen
Recombinant protein corresponding to the epidermal growth factor homology domain of human THBD.
Host
Mouse
Reactivity
Human
Form
Lyophilized
Isotype
IgG1
Recommend Usage
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from tissue culture supernatant (0.09% sodium azide)
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with steril distilled water, Store at 4°C for at least two months.
For long term storage store at -20°C or below.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
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Gene Info — THBD
Entrez GeneID
7056Gene Name
THBD
Gene Alias
CD141, THRM, TM
Gene Description
thrombomodulin
Omim ID
188040Gene Ontology
HyperlinkGene Summary
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq
Other Designations
CD141 antigen|OTTHUMP00000030415|fetomodulin
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Interactome
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Pathway
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Disease
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