Mouse monoclonal antibody raised against partial recombinant TSC2 .
Recombinant protein corresponding to the 240 amino acid at N-terminus of TSC2 .
Immunohistochemistry (1:25-1:50) The optimal working dilution should be determined by the end user.
Lyophilized from tissue culture supernatant (0.09% sodium azide)
Store at 4°C on dry atmosphere. After reconstitution with steril distilled water, Store at 4°C for at least two months. For long term storage store at -20°C or below. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq