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Last updated: 2016/11/27
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TSC2 monoclonal antibody, clone 3B4

  • Catalog # : MAB9683
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TSC2 .
  • Immunogen:
  • Recombinant protein corresponding to the 240 amino acid at N-terminus of TSC2 .
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Immunohistochemistry (1:25-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from tissue culture supernatant (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with steril distilled water, Store at 4°C for at least two months.
    For long term storage store at -20°C or below.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining for paraffin-embedded human cerebellum section using TSC2 monoclonal antibody, clone 3B4 (Cat # MAB9683). Note cytoplasmic staining of Purkinje cells.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 7249
  • Gene Name:
  • TSC2
  • Gene Alias:
  • FLJ43106,LAM,TSC4
  • Gene Description:
  • tuberous sclerosis 2
  • Gene Summary:
  • Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • tuberin
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