CD19 monoclonal antibody, clone BT51E.
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining for paraffin-embedded human bone marrow section using CD19 monoclonal antibody, clone BT51E. (Cat # MAB9625). Note membrane staining of B cells.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CD19.
Immunogen
Recombinant protein corresponding to C-terminus of human CD19.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
Immunohistochemistry (1:50)
Western Blot (1:50-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In tissue culture supernatant (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining for paraffin-embedded human bone marrow section using CD19 monoclonal antibody, clone BT51E. (Cat # MAB9625). Note membrane staining of B cells. -
Gene Info — CD19
Entrez GeneID
930Gene Name
CD19
Gene Alias
B4, MGC12802
Gene Description
CD19 molecule
Omim ID
107265Gene Ontology
HyperlinkGene Summary
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq
Other Designations
B-lymphocyte antigen CD19|CD19 antigen
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Interactome
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Pathway
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Disease
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Publication Reference
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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies.
Kevin R Parker, Denis Migliorini, Eric Perkey, Kathryn E Yost, Aparna Bhaduri, Puneet Bagga, Mohammad Haris, Neil E Wilson, Fang Liu, Khatuna Gabunia, John Scholler, Thomas J Montine, Vijay G Bhoj, Ravinder Reddy, Suyash Mohan, Ivan Maillard, Arnold R Kriegstein, Carl H June, Howard Y Chang, Avery D Posey Jr, Ansuman T Satpathy.
Cell 2020 Oct; 183(1):126.
Application：IHC-P, Human, Human brain.
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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies.
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