Mouse monoclonal antibody raised against partial recombinant MSH2.
Recombinant protein corresponding to a 304 amino acid fragment at N-terminus of human MSH2.
Immunohistochemistry (1:40-1:80) The optimal working dilution should be determined by the end user.
Lyophilized from tissue culture supernatant (0.09% sodium azide)
Store at 4°C on dry atmosphere. After reconstitution with steril distilled water, Store at 4°C for at least two months. For long term storage store at -20°C or below. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq