Mouse monoclonal antibody raised against partial recombinant MMP9.
Recombinant protein corresponding to a 134 amino acid fragment at C-terminus of human MMP9.
Immunohistochemistry (Frozen sections) (1:20-1:40) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:40-1:80) The optimal working dilution should be determined by the end user.
Lyophilized from tissue culture supernatant (0.09% sodium azide)
Store at 4°C on dry atmosphere. After reconstitution with steril distilled water, Store at 4°C for at least two months. For long term storage store at -20°C or below. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Immunohistochemical staining for paraffin-embedded human endometrial adenocarcinoma section using MMP9 monoclonal antibody, clone 15W2 (Cat # MAB9573). Note intense staining of malignant epithelial cells and their secretions.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq
92kD type IV collagenase,OTTHUMP00000031674,gelatinase B,macrophage gelatinase,matrix metalloproteinase 9,matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase),matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kD