MYOT monoclonal antibody, clone RSO34

Catalog # MAB9563

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Price

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Quantity

Size:1 mL
Price: USD $ 957.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining for paraffin-embedded human skeletal muscle section using MYOT monoclonal antibody, clone RSO34 (Cat # MAB9563). Note intense staining of muscle fibers.

  • Specification

    Product Description

    Mouse monoclonal antibody raised against partial recombinant MYOT.

    Immunogen

    Recombinant protein corresponding to 266 amino acids at C-terminus of human MYOT.

    Host

    Mouse

    Reactivity

    Human

    Form

    Lyophilized

    Isotype

    IgG1, kappa

    Recommend Usage

    Immunohistochemistry (Frozen sections) (1:20)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:40-1:80)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    Lyophilized from tissue culture supernatant (0.09% sodium azide)

    Storage Instruction

    Store at 4°C on dry atmosphere.
    After reconstitution with steril distilled water, Store at 4°C for at least two months.
    For long term storage store at -20°C or below.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining for paraffin-embedded human skeletal muscle section using MYOT monoclonal antibody, clone RSO34 (Cat # MAB9563). Note intense staining of muscle fibers.

    Immunohistochemistry (Frozen sections)

  • Gene Info — MYOT

    Entrez GeneID

    9499

    Gene Name

    MYOT

    Gene Alias

    LGMD1, LGMD1A, TTID

    Gene Description

    myotilin

    Omim ID

    159000 182920 604103 609200

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined

    Other Designations

    titin immunoglobulin domain protein (myotilin)

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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