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Last updated: 2016/12/4
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CASP9 monoclonal antibody, clone 2C9B11

  • Catalog # : MAB9555
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant CASP9.
  • Immunogen:
  • Recombinant protein corresponding to 134 amino acid near N-terminus of human CASP9.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunohistochemistry (1:20-1:40)
    Western Blot (1:25-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from tissue culture supernatant (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with steril distilled water, Store at 4°C for at least two months.
    For long term storage store at -20°C or below.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining for paraffin-embedded human rectal adenocarcinoma section using CASP9 monoclonal antibody, clone 2C9B11 (Cat # MAB9555). Note cytoplasmic staining of neoplastic epithelium.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 842
  • Gene Name:
  • CASP9
  • Gene Alias:
  • APAF-3,APAF3,CASPASE-9c,ICE-LAP6,MCH6
  • Gene Description:
  • caspase 9, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq
  • Other Designations:
  • ICE-like apoptotic protease 6,OTTHUMP00000002322,OTTHUMP00000002323,OTTHUMP00000044594,apoptotic protease MCH-6,apoptotic protease activating factor 3,caspase 9,caspase 9, apoptosis-related cysteine protease
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