CA9 monoclonal antibody, clone TH22
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining for paraffin-embedded human stomach section using CA9 monoclonal antibody, clone TH22 (Cat # MAB9551). Note intense membrane and cytoplasmic staining of mucus secreting cells of the deep glands.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CA9.
Immunogen
Recombinant protein corresponding to 118 amino acids of human CA9.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
Immunohistochemistry (1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In tissue culture supernatant (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining for paraffin-embedded human stomach section using CA9 monoclonal antibody, clone TH22 (Cat # MAB9551). Note intense membrane and cytoplasmic staining of mucus secreting cells of the deep glands. -
Gene Info — CA9
Entrez GeneID
768Gene Name
CA9
Gene Alias
CAIX, MN
Gene Description
carbonic anhydrase IX
Omim ID
603179Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq
Other Designations
OTTHUMP00000022773|RCC-associated protein G250|carbonic dehydratase
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Interactome
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