MPO monoclonal antibody, clone 59A5
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant MPO.
Immunogen
Recombinant protein corresponding to 101 amino acids from exon 7 of human MPO.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b, kappa
Recommend Usage
Immunohistochemistry (1:75-1:150)
The optimal working dilution should be determined by the end user.Storage Buffer
In tissue culture supernatant (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining for paraffin-embedded human bone marrow, granulocytic sarcoma section using MPO monoclonal antibody, clone 59A5 (Cat # MAB9544). Note intense cytoplasmic staining of malignant myeloid cells. -
Gene Info — MPO
Entrez GeneID
4353Gene Name
MPO
Gene Alias
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Gene Description
myeloperoxidase
Gene Ontology
HyperlinkGene Summary
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq
Other Designations
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Interactome
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Disease
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