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DYSF monoclonal antibody, clone Ham1/7B6

  • Catalog # : MAB9530
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of DYSF.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 1999-2016 of human DYSF.
  • Host:
  • Mouse
  • Reactivity:
  • Dog, Hamster, Human, Mouse, Pig, Rabbit, Rat
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (Frozen sections) (1:20-1:40)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from tissue culture supernatant (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with steril distilled water, Store at 4°C for at least two months.
    For long term storage store at -20°C or below.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 8291
  • Gene Name:
  • DYSF
  • Gene Alias:
  • FER1L1,FLJ00175,FLJ90168,LGMD2B
  • Gene Description:
  • dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
  • Gene Summary:
  • The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • dysferlin,dystrophy-associated fer-1-like 1
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